The catalogue

Browse entries

Search the complete collection, narrow it by category or status, choose how it is ordered, and switch between detailed cards and a compact index.

View

Showing all 297 entries

Not a fact anymore

Every acid contains oxygen.

What we know now

Many acids contain oxygen, but some do not. Hydrochloric acid, hydrobromic acid, and hydroiodic acid are familiar counterexamples.

Status
Overturned
Category
Chemistry
Accepted for
≈35 years
Changed approximately
1810s
Read the evidence →

Not a fact anymore

Adult human heart-muscle cells are permanently post-mitotic and are never replaced.

What we know now

Adult human heart-muscle cells, called cardiomyocytes, do renew, but very slowly. Estimates suggest that roughly 1% are replaced each year in younger adults, with the rate falling with age. That is far too little to rebuild the large amount of muscle lost in a major heart attack.

Status
Overturned
Category
Medicine
Accepted for
Not quantified
Changed approximately
Late 20th century–2000s
Read the evidence →

Not a fact anymore

Adult mammalian brains cannot produce new neurons.

What we know now

Adult brains can produce new neurons, a process called neurogenesis, in limited regions in many animals. How much new-neuron formation continues in adult humans—especially later in life—remains actively debated.

Status
Overturned
Category
Neuroscience
Accepted for
Not quantified
Changed approximately
1960s–1990s
Read the evidence →

Not a fact anymore

Atmospheric temperature always decreases as altitude increases.

What we know now

Temperature does not keep falling all the way up through the atmosphere. It usually decreases through the troposphere, the lowest layer where most weather occurs, but begins rising through much of the stratosphere because ozone absorbs ultraviolet sunlight and converts some of that energy to heat.

Status
Overturned
Accepted for
≈69 years
Changed approximately
1902–1930s
Read the evidence →

Not a fact anymore

Base metals are immature or imperfect forms of metal that naturally ripen toward gold, and alchemical processes can accelerate that maturation.

What we know now

Copper, iron, lead, silver, gold, and other metals are distinct chemical elements defined by atomic number. Ordinary chemical reactions cannot turn one element into another; elemental transmutation requires nuclear processes.

Status
Superseded
Category
Chemistry
Accepted for
Not quantified
Changed approximately
17th–19th centuries
Read the evidence →

Not a fact anymore

Before European contact, Amazonia was largely pristine wilderness occupied only by small, scattered groups with little effect on the landscape.

What we know now

Many parts of Amazonia were substantially shaped by Indigenous societies before European contact. Archaeologists have found settlements, roads, canals, raised fields, large earthworks, engineered soils, and long-term forest management. The scale of occupation varied greatly across the enormous basin.

Status
Narrowed
Category
Archaeology
Accepted for
≈45 years
Changed approximately
1990s–present
Read the evidence →

Not a fact anymore

Beta blockers are dangerous and should not be used in patients with chronic heart failure.

What we know now

Selected beta blockers are standard treatment for stable heart failure with reduced ejection fraction, meaning the heart pumps out a smaller-than-normal share of the blood in its main chamber with each beat. When introduced carefully, these drugs reduce hospitalization and improve survival.

Status
Overturned
Category
Medicine
Accepted for
≈20 years
Changed approximately
1980s–2000s
Read the evidence →

Not a fact anymore

Bodily changes acquired through use, disuse, or environmental conditions were widely thought to be inherited and to direct evolutionary change.

What we know now

Evolution mainly works through inherited variation: genetic differences that can be passed from parents to offspring. Changes acquired during an individual's life—such as stronger muscles from exercise or the loss of a limb—are not generally written back into the inherited genetic material. Some environmental effects can persist across generations, but they are much narrower than classical Lamarckian inheritance.

Status
Superseded
Category
Evolution
Accepted for
Not quantified
Changed approximately
1880s–1930s
Read the evidence →

Not a fact anymore

Bone is primarily a structural and mineral-regulating organ, not an endocrine organ that signals to distant tissues.

What we know now

Bone is not only structural tissue. It is constantly rebuilt, stores and releases minerals, produces blood cells in its marrow, and also sends chemical signals to distant organs. One well-established example is FGF23, a hormone made mainly by bone cells that helps the kidneys control phosphate and vitamin D.

Status
Superseded
Category
Medicine
Accepted for
Not quantified
Changed approximately
Late 20th century–2000s
Read the evidence →

Not a fact anymore

Breast milk is menstrual blood redirected to the breasts and transformed after childbirth.

What we know now

Milk is synthesized by mammary epithelial cells from nutrients and water supplied through the bloodstream, under hormonal regulation involving prolactin, oxytocin, estrogen, progesterone, and other signals. It is not transformed menstrual blood.

Status
Overturned
Category
Medicine
Accepted for
Not quantified
Changed approximately
18th–19th centuries, with modern endocrine physiology later completing the explanation
Read the evidence →

Not a fact anymore

California was an island separated from mainland North America.

What we know now

California is part of mainland North America. Baja California is a peninsula bounded by the Pacific Ocean and the Gulf of California, while the modern U.S. state of California is continuous with the continent.

Status
Corrected
Accepted for
≈83 years
Changed approximately
Kino's overland expeditions, 1698–1701; peninsula map published in Europe in 1705
Read the evidence →

Not a fact anymore

Cervical cancer is unrelated to viral infection.

What we know now

Nearly all cervical cancers are caused by persistent infection with high-risk types of human papillomavirus, or HPV. HPV is very common and most infections clear on their own, but some high-risk infections persist and can gradually disrupt the controls that keep cervical cells from growing abnormally.

Status
Overturned
Category
Medicine
Accepted for
≈33 years
Changed approximately
1980s–1990s
Read the evidence →

Not a fact anymore

Changes in gravity are transmitted instantaneously across any distance.

What we know now

Changes in gravity do not act everywhere at once. In general relativity, gravity is part of the structure of spacetime, and changes in the gravitational field propagate at the speed of light. Rapidly accelerating masses can produce traveling disturbances called gravitational waves.

Status
Superseded
Category
Physics
Accepted for
≈265 years
Changed approximately
1915 onward
Read the evidence →

Not a fact anymore

Chemically inert CFCs released near the ground cannot damage the stratospheric ozone layer.

What we know now

CFCs—chlorofluorocarbons once widely used in refrigerants and aerosol propellants—are so stable near the ground that they can survive long enough to reach the stratosphere. There, ultraviolet sunlight breaks them apart and releases chlorine, which can destroy many ozone molecules in repeated chemical reactions.

Status
Overturned
Accepted for
≈39 years
Changed approximately
1974–1980s
Read the evidence →

Not a fact anymore

Children learn language entirely by imitating adults and being rewarded for correct speech.

What we know now

Imitation, feedback, and reinforcement contribute to language learning, but they do not explain it alone. Children detect patterns, infer rules, generalize beyond what they hear, and develop language through interacting cognitive, social, and biological processes.

Status
Superseded
Category
Psychology
Accepted for
≈24 years
Changed approximately
1950s–present
Read the evidence →

Not a fact anymore

Cigarette smoking does not cause lung cancer.

What we know now

Cigarette smoking is the leading cause of lung cancer. Risk rises with cumulative exposure, falls after quitting, and is supported by converging epidemiological, pathological, toxicological, and molecular evidence.

Status
Overturned
Accepted for
≈35 years
Changed approximately
1950s–1964
Read the evidence →

Not a fact anymore

A coral reef is a solid mass of living coral.

What we know now

Only a thin outer layer of a coral colony is living tissue. Reef frameworks contain accumulated calcium-carbonate skeletons, dead coral, sediments, algae, sponges, microbes, and many other organisms.

Status
Corrected
Accepted for
≈42 years
Changed approximately
19th–20th centuries
Read the evidence →

Not a fact anymore

Dreams occur only during REM sleep.

What we know now

Dreaming can occur during both REM and non-REM sleep. REM dreams are often more vivid and story-like, but non-REM awakenings can also produce detailed dream reports.

Status
Overturned
Category
Neuroscience
Accepted for
≈7 years
Changed approximately
1960s–2000s
Read the evidence →

Not a fact anymore

Each gene produces exactly one protein.

What we know now

One gene can produce several RNA or protein products through alternative splicing, different promoters, and other forms of RNA processing. Some genes produce functional RNA rather than protein.

Status
Superseded
Category
Genetics
Accepted for
≈32 years
Changed approximately
1970s–2000s
Read the evidence →

Not a fact anymore

Earth's entire metallic core is liquid.

What we know now

Earth's core has two main layers: a liquid outer core surrounding a solid inner core. Earthquake waves reveal the difference because different kinds of seismic waves travel differently through solids and liquids.

Status
Narrowed
Accepted for
≈21 years
Changed approximately
1936–1970s
Read the evidence →

Not a fact anymore

Earth's magnetic field is produced by permanent magnetism in its iron-rich core.

What we know now

Earth's main magnetic field is generated by a geodynamo in the liquid outer core. Hot, electrically conducting metal moves through the core, creating electric currents that continually sustain the magnetic field. The core is far too hot to behave like an ordinary permanent bar magnet.

Status
Overturned
Accepted for
≈269 years
Changed approximately
1910s–1950s
Read the evidence →

Not a fact anymore

An embryo already exists in essentially preformed miniature organization, and development mainly unfolds or enlarges structures that are already present.

What we know now

Embryonic form emerges progressively through cell division, differentiation, signaling, gene regulation, morphogenesis, and interactions among tissues. The organism is not present as a complete miniature individual inside the egg or sperm.

Status
Overturned
Category
Biology
Accepted for
≈130 years
Changed approximately
Late 18th–early 19th centuries
Read the evidence →

Not a fact anymore

The equatorial 'torrid zone' is too hot for humans to inhabit.

What we know now

Humans live throughout the tropics and near the equator. Equatorial regions are generally warm, but habitability depends on rainfall, altitude, ecology, infrastructure, adaptation, and many other factors. There is no lethal solar heat barrier around the equator.

Status
Overturned
Accepted for
Not quantified
Changed approximately
Late medieval–15th-century travel and exploration
Read the evidence →

Not a fact anymore

European mecC-MRSA lineages arose during the modern antibiotic era because medical or veterinary antibiotic use selected for methicillin resistance.

What we know now

Some European MRSA lineages carrying the resistance gene mecC arose long before antibiotics were used in medicine. Hedgehogs carry these bacteria alongside a skin fungus that naturally produces β-lactam antibiotics, creating an environment that can favor resistant bacteria without human antibiotic use.

Status
Corrected
Category
Microbiology
Accepted for
Not quantified
Changed approximately
2022
Read the evidence →

Not a fact anymore

Fibonacci leaf spirals were an ancient pattern inherited from the earliest leafy land plants.

What we know now

Fibonacci phyllotaxis was not universal among the earliest leafy plants. A 407-million-year-old lycophyte had only non-Fibonacci spirals in the reconstructed shoots, supporting later and probably independent evolution of Fibonacci-dominated patterns in major plant lineages.

Status
Overturned
Category
Botany
Accepted for
Not quantified
Changed approximately
2023
Read the evidence →

Not a fact anymore

Fomalhaut b is a directly imaged exoplanet.

What we know now

The source called Fomalhaut b is best explained as an expanding dust cloud produced by a collision between large planetesimals, not as a planet. Hubble watched the source fade, spread out, and move in a way consistent with dispersing collision debris.

Status
Reclassified
Category
Astronomy
Accepted for
≈12 years
Changed approximately
2020
Read the evidence →

Not a fact anymore

Food webs were expected to depend ultimately on photosynthetic primary production powered by sunlight.

What we know now

Some ecosystems do not begin with sunlight. Certain microorganisms can make organic matter using energy released by chemical reactions rather than photosynthesis. This process, called chemosynthesis, can support entire food webs in dark environments such as deep-sea hydrothermal vents.

Status
Overturned
Accepted for
Not quantified
Changed approximately
1977–early 1980s
Read the evidence →

Not a fact anymore

Fungi are plants.

What we know now

Fungi form their own major branch of life. Unlike plants, they do not use photosynthesis to make food; they release digestive enzymes into their surroundings and absorb the resulting nutrients. Molecular evidence also shows that fungi are evolutionarily closer to animals than to plants.

Status
Reclassified
Category
Biology
Accepted for
≈216 years
Changed approximately
1969
Read the evidence →

Not a fact anymore

Genes pass only from parents to their offspring.

What we know now

Genes usually pass vertically from parents to offspring, but DNA can also move horizontally between unrelated organisms. This is especially common in microbes and can spread useful traits, including antibiotic resistance, without reproduction.

Status
Narrowed
Category
Genetics
Accepted for
≈96 years
Changed approximately
1920s–present
Read the evidence →

Not a fact anymore

Giant sauropod dinosaurs were too heavy to support themselves on land and therefore had to live largely submerged in water.

What we know now

Sauropods were primarily terrestrial animals with limbs, feet and skeletons adapted to bearing enormous loads on land. They could enter water and probably could swim, but deep-water immersion was not required to support their bodies; their air-filled skeletal and respiratory system actually made them unusually buoyant and potentially unstable when floating.

Status
Overturned
Category
Paleontology
Accepted for
≈75 years
Changed approximately
1960s–1975
Read the evidence →

Not a fact anymore

Glial cells are merely passive glue and support for the neurons that perform all meaningful nervous-system processing.

What we know now

Glial cells do much more than hold neurons in place. Different kinds of glia insulate nerve fibers, control the chemical environment around neurons, supply metabolic support, help shape synapses, regulate local blood flow, guide development, and perform immune functions in the nervous system.

Status
Overturned
Category
Neuroscience
Accepted for
≈115 years
Changed approximately
1960s–present
Read the evidence →

Not a fact anymore

The gravitating mass of galaxies and galaxy clusters can be accounted for almost entirely by the stars and gas that astronomers can observe directly.

What we know now

The stars, glowing gas, planets, and other ordinary matter we can observe directly make up only a small part of the modern cosmic inventory. Gravity requires much more dark matter around galaxies and clusters, while cosmological measurements indicate that dark energy contributes an even larger share of the universe's total energy density.

Status
Superseded
Category
Cosmology
Accepted for
≈55 years
Changed approximately
1930s–1970s, consolidated later
Read the evidence →

Not a fact anymore

The great ocean fisheries are effectively inexhaustible because human catches are insignificant compared with the abundance of fish.

What we know now

Fishing can reduce marine populations below productive levels, collapse individual stocks, alter food webs, and cause long-lasting depletion. Whether a stock recovers depends on biology, habitat, environmental conditions, and management.

Status
Overturned
Category
Ecology
Accepted for
≈120 years
Changed approximately
Mid–late 20th century
Read the evidence →

Not a fact anymore

Healthy lungs are sterile and contain no microbial community.

What we know now

Healthy lungs are not completely sterile. The lower airways contain small numbers of microbes, forming a low-density microbiome shaped by inhaled organisms, tiny amounts of material entering from the mouth and throat, immune clearance, and local conditions.

Status
Overturned
Category
Medicine
Accepted for
≈125 years
Changed approximately
2010s
Read the evidence →

Not a fact anymore

Heavenly bodies are made from a special incorruptible substance called aether or quintessence, rather than the matter found on Earth.

What we know now

The Sun, stars, planets, moons, asteroids, and comets are made from the same chemical elements and governed by the same fundamental physics studied on Earth, although their compositions and physical states differ.

Status
Superseded
Category
Astronomy
Accepted for
Not quantified
Changed approximately
17th–19th centuries
Read the evidence →

Not a fact anymore

Homo floresiensis was merely a modern human with a disease or growth disorder.

What we know now

Most specialists recognize Homo floresiensis as a distinct archaic human species rather than a diseased modern human. Its unusual anatomy appears in more than one individual and includes a combination of primitive traits that a single disorder does not explain well.

Status
Overturned
Accepted for
≈12 years
Changed approximately
Late 2000s–present
Read the evidence →

Not a fact anymore

The human brain evolved by stacking three independently functioning brains: reptilian, emotional mammalian, and rational human.

What we know now

Vertebrate brains evolved through modification and reorganization of shared structures and interconnected networks. Reptiles possess homologues of structures called limbic or cortical in mammals, and cognition, emotion, and basic regulation are not confined to independent evolutionary layers.

Status
Superseded
Category
Neuroscience
Accepted for
≈35 years
Changed approximately
1980s–present
Read the evidence →

Not a fact anymore

The human liver is divided into five distinct lobes.

What we know now

Standard anatomical description recognizes four named anatomical lobes of the human liver: right, left, caudate, and quadrate. Modern surgical anatomy also divides the liver functionally into vascular segments.

Status
Corrected
Category
Medicine
Accepted for
≈1,393 years
Changed approximately
1540–1543
Read the evidence →

Not a fact anymore

Identical twins remain genetically identical throughout life.

What we know now

Identical twins begin with nearly the same inherited DNA because they develop from the same fertilized egg. After the embryo splits, however, new DNA mutations can arise independently in either twin, so their genomes become slightly different over time.

Status
Corrected
Category
Genetics
Accepted for
≈93 years
Changed approximately
2000s–present
Read the evidence →

Not a fact anymore

Illness is caused by an imbalance among the body's four humors: blood, phlegm, yellow bile, and black bile.

What we know now

Diseases have many distinct causes and mechanisms, including infections, genetic changes, immune dysfunction, nutritional deficiencies, environmental exposures, degeneration, and injury. The four humors are not anatomical substances whose balance governs health.

Status
Superseded
Category
Medicine
Accepted for
≈1,650 years
Changed approximately
17th–19th centuries
Read the evidence →

Not a fact anymore

Immune tolerance was thought to prevent self-directed immune reactions from becoming a major cause of disease.

What we know now

Antibodies are immune proteins that recognize specific targets. Those targets are often foreign, such as parts of microbes or their toxins, but antibodies and immune cells can also recognize the body’s own tissues. Normally the immune system restrains these reactions; when that control fails, autoimmune disease can result.

Status
Narrowed
Category
Immunology
Accepted for
Not quantified
Changed approximately
1940s–1960s
Read the evidence →

Not a fact anymore

Legume plants enrich soil by fixing atmospheric nitrogen on their own.

What we know now

Legumes such as peas, beans, and clover usually obtain usable nitrogen through a partnership with bacteria called rhizobia. The bacteria live in specialized root nodules and convert nitrogen gas from the air into chemical forms the plant can use; the plant supplies them with energy and shelter.

Status
Corrected
Category
Botany
Accepted for
≈75 years
Changed approximately
1880s–1890s
Read the evidence →

Not a fact anymore

Light travels instantaneously.

What we know now

Light propagates through vacuum at a finite speed of exactly 299,792,458 metres per second. This speed is a fundamental constant and the maximum speed for causal influence in relativity.

Status
Overturned
Category
Physics
Accepted for
≈39 years
Changed approximately
1676–19th century
Read the evidence →

Not a fact anymore

All living things fit naturally into five kingdoms: animals, plants, fungi, protists, and monerans.

What we know now

The five-kingdom system—animals, plants, fungi, protists, and monerans—does not accurately represent all major evolutionary relationships. DNA and RNA comparisons showed that organisms once grouped together as Monera actually include two very different lineages, Bacteria and Archaea, while 'Protista' contains many distantly related branches.

Status
Superseded
Category
Evolution
Accepted for
≈9 years
Changed approximately
1970s–present
Read the evidence →

Not a fact anymore

Long-lived dense planetary rings can survive only inside their parent body’s Roche limit.

What we know now

Quaoar, a small body orbiting beyond Neptune, has a dense ring far outside its classical Roche limit, the region where tidal forces can prevent loose ring material from assembling into a moon. The Roche limit is therefore not an absolute outer boundary for dense rings.

Status
Narrowed
Accepted for
Not quantified
Changed approximately
2023
Read the evidence →

Not a fact anymore

Luxuriant tropical rainforest was widely taken as evidence that the underlying soil was exceptionally fertile and could remain highly productive after clearing.

What we know now

Tropical soils vary enormously. Many rainforests grow on old, deeply weathered soils that are poor in readily available nutrients, with productivity sustained by rapid recycling through biomass, litter, roots, fungi, and microbes. Volcanic, alluvial, and younger tropical soils can be naturally fertile.

Status
Narrowed
Category
Ecology
Accepted for
Not quantified
Changed approximately
1930s–mid-20th century
Read the evidence →

Not a fact anymore

Most major rocks, including granite and many volcanic rocks, precipitated from a primordial ocean that once covered Earth.

What we know now

Rocks form in several fundamentally different ways. Igneous rocks such as basalt and granite crystallize from molten rock; sedimentary rocks form from deposited material or substances precipitated from water; and metamorphic rocks form when older rocks are transformed by heat, pressure, or fluids.

Status
Overturned
Accepted for
≈23 years
Changed approximately
Late 18th–early 19th centuries
Read the evidence →

Not a fact anymore

Mammalian spinal evolution was a simple transition from reptile-like side-to-side bending in early synapsids to mammal-like up-and-down bending.

What we know now

Fossil synapsid vertebrae do not support a simple shift from lizard-like side-to-side bending to mammal-like up-and-down bending. Early synapsids appear to have had relatively stiff spines, with later mammals evolving several kinds of regional movement and specialization.

Status
Superseded
Category
Evolution
Accepted for
Not quantified
Changed approximately
2021
Read the evidence →

Not a fact anymore

Mass and energy are entirely separate conserved quantities.

What we know now

Mass and energy are related rather than completely separate. A body's rest mass corresponds to energy through E = mc², and energy stored inside a system contributes to that system's mass. Nuclear reactions make this connection large enough to measure easily.

Status
Superseded
Category
Physics
Accepted for
≈205 years
Changed approximately
1905 onward
Read the evidence →

Not a fact anymore

Migraine is caused simply by blood vessels constricting and then dilating.

What we know now

Migraine is a neurological disorder involving brain networks, sensory processing, the trigeminal nerve system, signaling molecules, and blood vessels. Changes in vessel size can occur during an attack, but dilation by itself is neither necessary nor enough to explain migraine.

Status
Superseded
Category
Neuroscience
Accepted for
≈45 years
Changed approximately
1980s–present
Read the evidence →

Not a fact anymore

The Milky Way is destined to collide and merge with the Andromeda galaxy.

What we know now

A future Milky Way–Andromeda merger remains plausible, but it is no longer considered inevitable. Simulations using newer Hubble and Gaia measurements, updated galaxy masses, and the gravitational influence of M33 and the Large Magellanic Cloud find roughly even odds that the two large galaxies will not merge within the next 10 billion years.

Status
Narrowed
Category
Astronomy
Accepted for
≈13 years
Changed approximately
2025
Read the evidence →

Not a fact anymore

Mitochondria and chloroplasts developed entirely within complex cells and have no evolutionary relationship to bacteria.

What we know now

Mitochondria and chloroplasts descend from bacteria that once lived independently. Ancient host cells took those bacteria inside, the partnership became permanent, and over evolutionary time the former bacteria became organelles—specialized structures inside the cell.

Status
Overturned
Category
Evolution
Accepted for
≈42 years
Changed approximately
1960s–1980s
Read the evidence →

Not a fact anymore

The Moon is completely dry.

What we know now

The Moon is extremely dry compared with Earth, but it is not water-free. Small amounts of water and hydroxyl are bound in lunar minerals and volcanic glass, and water ice exists in some permanently shadowed regions near the poles.

Status
Overturned
Category
Astronomy
Accepted for
≈39 years
Changed approximately
1990s–2010s
Read the evidence →

Not a fact anymore

The Moon’s youngest mare volcanism required a KREEP-rich mantle source enriched in heat-producing elements.

What we know now

Chang’e-5 returned lunar basalts about 2 billion years old whose chemistry points to a mantle source with little KREEP contribution. KREEP—material rich in potassium, rare-earth elements, phosphorus, and heat-producing radioactive elements—is therefore not required as the direct source of the Moon’s youngest volcanism.

Status
Narrowed
Accepted for
Not quantified
Changed approximately
2021
Read the evidence →

Not a fact anymore

Natural background radiation is an important source of the spontaneous mutations that fuel evolution.

What we know now

Ionizing radiation can certainly mutate DNA, but at ordinary background levels its contribution to spontaneous mutation appears to be small. In a Lenski-style E. coli experiment beneath 1,700 m of rock, the absorbed dose rate fell from 214 to 26 nGy per hour, yet adaptation did not measurably slow over 500 generations. Replication errors and endogenous DNA chemistry provide abundant mutation sources even when ambient radiation is stripped away; ultra-low radiation can still affect cell physiology.

Status
Narrowed
Category
Evolution
Accepted for
Not quantified
Changed approximately
2010s
Read the evidence →

Not a fact anymore

Neutrinos are massless.

What we know now

Neutrinos have a tiny but nonzero mass. They come in different types, called flavors, and can change from one flavor into another while traveling. That oscillation can occur only if the underlying neutrino states do not all have the same mass.

Status
Overturned
Category
Physics
Accepted for
≈48 years
Changed approximately
1998–2001
Read the evidence →

Not a fact anymore

Open-ocean regions rich in nitrate and phosphate were thought to contain enough iron that iron deficiency could not explain their low phytoplankton productivity.

What we know now

Some ocean regions contain plenty of major nutrients such as nitrate and phosphate but still support surprisingly little phytoplankton growth. In several of these regions, the missing ingredient is iron: tiny amounts of bioavailable iron can limit the microscopic algae that form the base of the food web.

Status
Corrected
Category
Oceanography
Accepted for
Not quantified
Changed approximately
1980s–1990s
Read the evidence →

Not a fact anymore

An optical microscope can never resolve detail smaller than the diffraction limit.

What we know now

Ordinary optical microscopes cannot cleanly separate two nearby details once their blurred light patterns overlap below the diffraction limit. Super-resolution microscopy can recover finer information by changing how fluorescent molecules are switched on, measured, and reconstructed rather than by making conventional diffraction disappear.

Status
Narrowed
Category
Measurement
Accepted for
≈119 years
Changed approximately
1990s–2000s
Read the evidence →

Not a fact anymore

Oxidation always means adding oxygen to a substance.

What we know now

Oxidation does not require oxygen. In modern chemistry, oxidation means that a substance loses electrons, or equivalently that its oxidation state increases. Oxygen often causes oxidation, but chlorine, metal ions, and many other chemicals can do the same.

Status
Superseded
Category
Chemistry
Accepted for
≈135 years
Changed approximately
Late 19th–20th century
Read the evidence →

Not a fact anymore

The placenta is a complete barrier that protects the fetus from medicines, chemicals, and infections in the mother's blood.

What we know now

The placenta is a selective exchange organ, not an impermeable wall. It allows oxygen and nutrients to reach the fetus and waste products to leave, but many medicines, alcohol, environmental chemicals, antibodies, and some infections can also cross it or affect its function.

Status
Narrowed
Category
Medicine
Accepted for
≈76 years
Changed approximately
1940s–1960s
Read the evidence →

Not a fact anymore

Planetary and stellar configurations exert physical influences that can cause disease and should guide medical diagnosis, prognosis, and treatment.

What we know now

Disease arises through biological, genetic, environmental, behavioral, nutritional, toxic, traumatic, and social mechanisms. Planetary positions and zodiacal configurations do not exert clinically meaningful causal effects on disease or determine appropriate treatment.

Status
Superseded
Category
Medicine
Accepted for
Not quantified
Changed approximately
17th–19th centuries
Read the evidence →

Not a fact anymore

Pluto is the ninth planet of the Solar System.

What we know now

Under the International Astronomical Union's 2006 definition, Pluto is a dwarf planet because it has not cleared the neighbourhood around its orbit. The Solar System has eight objects formally classified as planets.

Status
Reclassified
Category
Astronomy
Accepted for
≈76 years
Changed approximately
2006
Read the evidence →

Not a fact anymore

A pregnant woman's intense sights, fears, desires, or imagination can physically mark or deform the developing fetus.

What we know now

Congenital anomalies arise from genetic, chromosomal, developmental, infectious, environmental, nutritional, metabolic, or other biological causes. A mother's visual impressions or imagination do not imprint corresponding physical shapes or marks on the fetus.

Status
Overturned
Category
Medicine
Accepted for
Not quantified
Changed approximately
18th century
Read the evidence →

Not a fact anymore

Prokaryotes were treated as one fundamental group, with organisms now called archaea classified among the bacteria.

What we know now

Cells without a nucleus are not all one kind of organism. They include Bacteria and Archaea, two deeply different evolutionary lineages. Archaea can resemble bacteria under a microscope but differ in their cell membranes, genes, and much of the molecular machinery inside the cell.

Status
Reclassified
Category
Microbiology
Accepted for
Not quantified
Changed approximately
1977–1990
Read the evidence →

Not a fact anymore

A properly healing wound should produce pus.

What we know now

Pus usually indicates an inflammatory response to infection or tissue destruction. Modern wound care aims to prevent or control infection rather than encourage suppuration.

Status
Overturned
Category
Medicine
Accepted for
≈667 years
Changed approximately
1860s–early 20th century
Read the evidence →

Not a fact anymore

Protons and neutrons are fundamental particles with no internal structure.

What we know now

Protons and neutrons are not fundamental particles. They are composite particles built from quarks and gluons, whose interactions are governed by the strong nuclear force. Much of a proton or neutron's mass comes from the energy of this internal activity rather than simply from the masses of its quarks.

Status
Overturned
Category
Physics
Accepted for
≈33 years
Changed approximately
1960s–1970s
Read the evidence →

Not a fact anymore

Repeated medical X-ray exposure causes no cumulative biological harm.

What we know now

X-rays are ionizing radiation: they carry enough energy to remove electrons from atoms and can therefore damage tissue and DNA. Radiation dose accumulates across exposures, although the risk from an individually justified modern diagnostic examination is usually small compared with its clinical benefit.

Status
Overturned
Category
Medicine
Accepted for
≈35 years
Changed approximately
1900s–1950s
Read the evidence →

Not a fact anymore

Respiratory particles can be divided into “droplets” and “aerosols” using one fixed particle-size cutoff.

What we know now

Respiratory particles form a continuous range of sizes rather than two clean categories separated by one universal cutoff. Larger particles tend to settle faster and smaller ones tend to remain airborne longer, but their behavior also depends on evaporation, airflow, humidity, and how they are produced.

Status
Superseded
Accepted for
Not quantified
Changed approximately
2024
Read the evidence →

Not a fact anymore

Rickets is caused primarily by infection or poor hygiene.

What we know now

Most nutritional rickets results from inadequate vitamin D, calcium, or phosphate. These shortages impair bone mineralization—the hardening of growing bone with calcium- and phosphate-rich mineral. Limited sunlight, diet, malabsorption, and some inherited disorders can all contribute.

Status
Overturned
Category
Medicine
Accepted for
≈69 years
Changed approximately
1910s–1930s
Read the evidence →

Not a fact anymore

RNA cannot serve as hereditary material.

What we know now

Many viruses use RNA genomes, and RNA molecules can store, copy, and transmit hereditary information. Cellular organisms use DNA as their principal long-term genome, but heredity is not chemically restricted to DNA.

Status
Overturned
Category
Genetics
Accepted for
≈12 years
Changed approximately
1956–1957
Read the evidence →

Not a fact anymore

Rubber, cellulose, and other polymers are loose aggregates of small molecules rather than giant covalently bonded molecules.

What we know now

Polymers are macromolecules: very large molecules made from many smaller building blocks joined by covalent bonds into long chains or networks. Materials such as rubber and cellulose are not merely loose clusters of ordinary small molecules.

Status
Overturned
Category
Chemistry
Accepted for
≈45 years
Changed approximately
1920s–1930s
Read the evidence →

Not a fact anymore

Slime molds are fungi.

What we know now

Slime molds are not true fungi. The name covers several groups of amoeba-like eukaryotes that crawl and feed as individual cells or moving masses before producing spore-bearing structures that happen to resemble fungal fruiting bodies.

Status
Reclassified
Category
Microbiology
Accepted for
≈140 years
Changed approximately
Late 20th century–present
Read the evidence →

Not a fact anymore

Some shell-, bone-, or organism-shaped stones are generated inside rocks by mineral or 'plastic' forces rather than being the remains of once-living organisms.

What we know now

Fossils are preserved remains, impressions, traces, or other evidence of past life. They typically form when organisms or traces are buried and preserved in sediment, sometimes with later mineral replacement.

Status
Overturned
Accepted for
Not quantified
Changed approximately
Late 17th–18th centuries
Read the evidence →

Not a fact anymore

Standard laboratory methods can culture most microorganisms found in nature.

What we know now

Traditional laboratory culture—growing microorganisms under controlled conditions—recovers only a fraction of environmental microbes. Many require unusual nutrients, partner organisms, host cells, slow growth, low nutrient levels, or conditions that are difficult to reproduce.

Status
Overturned
Category
Microbiology
Accepted for
≈100 years
Changed approximately
1970s–2000s
Read the evidence →

Not a fact anymore

Stonehenge was built by Druids.

What we know now

Stonehenge was constructed in stages by Neolithic and Bronze Age communities, with the principal stone settings raised around 2500 BCE. Historically documented Druids lived much later.

Status
Overturned
Category
Archaeology
Accepted for
≈265 years
Changed approximately
Late 19th–20th century
Read the evidence →

Not a fact anymore

The Sun's outer atmosphere must be cooler than its visible surface.

What we know now

The Sun's corona, its thin outer atmosphere, reaches roughly one to several million kelvin—far hotter than the visible surface below, which is about 5,800 K. The corona is extremely thin, so high temperature does not mean it contains more total heat than the denser layers beneath it.

Status
Overturned
Category
Astronomy
Accepted for
≈90 years
Changed approximately
1939–1942
Read the evidence →

Not a fact anymore

Synaptic transmission was widely expected to continue electrically across the junction between excitable cells.

What we know now

A synapse is the junction where one nerve cell communicates with another cell. At most vertebrate synapses, the first cell releases chemical messengers called neurotransmitters, which bind to receptors on the next cell. Some synapses are genuinely electrical and pass current directly between cells through connecting channels.

Status
Narrowed
Category
Neuroscience
Accepted for
Not quantified
Changed approximately
1921–1950s
Read the evidence →

Not a fact anymore

Thalidomide is safe to use during pregnancy.

What we know now

Thalidomide is a powerful human teratogen. Exposure during sensitive stages of early pregnancy can cause severe limb, ear, eye, cardiac, and internal-organ defects, and pregnancy must be rigorously prevented during treatment.

Status
Overturned
Category
Medicine
Accepted for
≈4 years
Changed approximately
1961–1962
Read the evidence →

Not a fact anymore

Thunderstorms and lightning are produced by the ignition or explosion of sulfurous, nitrous, or other combustible vapors in the atmosphere.

What we know now

Lightning is a large electrical discharge produced after charge separation creates sufficiently strong electric fields within storms or between clouds and the ground. Thunder is the acoustic shock produced by rapid heating and expansion along the lightning channel.

Status
Superseded
Accepted for
≈52 years
Changed approximately
Mid-18th century
Read the evidence →

Not a fact anymore

The thymus is a useless vestigial organ, especially after childhood.

What we know now

The thymus is a training and selection site for developing T cells, immune cells that help coordinate and carry out targeted immune responses. It helps preserve cells that can respond to threats while eliminating or restraining many that react strongly against the body's own tissues. Its activity declines with age but does not become meaningless.

Status
Overturned
Category
Medicine
Accepted for
≈111 years
Changed approximately
1961–1970s
Read the evidence →

Not a fact anymore

Titan’s outward tidal migration should be extremely slow because it orbits far from Saturn.

What we know now

Titan is slowly moving away from Saturn, but much faster than older tidal models predicted for such a distant moon. Cassini measurements support a process called resonance locking, in which Titan can remain strongly coupled to changing oscillations inside Saturn and continue receiving tidal energy.

Status
Corrected
Accepted for
Not quantified
Changed approximately
2020
Read the evidence →

Not a fact anymore

Transmissible infectious agents were expected to require DNA or RNA to store and propagate biological information.

What we know now

Prions are infectious agents made mainly of protein and carry no DNA or RNA genome of their own. A misfolded prion protein can force normally folded copies of the same protein in the host to change into the same abnormal shape, allowing the harmful form to spread.

Status
Overturned
Category
Medicine
Accepted for
Not quantified
Changed approximately
1982–1997
Read the evidence →

Not a fact anymore

The universe is static and does not expand.

What we know now

The universe is expanding on large scales. Distant galaxies generally recede in a relationship between their distance and redshift, and the expansion rate has changed over cosmic time.

Status
Overturned
Category
Astronomy
Accepted for
≈79 years
Changed approximately
1920s–1930s
Read the evidence →

Not a fact anymore

A vast southern continent must exist to balance the large landmasses of the Northern Hemisphere.

What we know now

Earth's continents are products of plate tectonics and geological history; there is no physical requirement for land area to be symmetrically balanced between hemispheres. Antarctica exists, but it is not the enormous temperate Terra Australis imagined on early maps.

Status
Overturned
Accepted for
Not quantified
Changed approximately
18th-century Pacific exploration
Read the evidence →

Not a fact anymore

Vision occurs because visual rays or a visual power travels outward from the eyes to the object being seen.

What we know now

Light from external sources is emitted or reflected by objects, enters the eye, is focused onto the retina, and is converted by photoreceptors into neural signals processed by the visual system.

Status
Superseded
Category
Physics
Accepted for
Not quantified
Changed approximately
13th-century European optics after the Latin reception of Ibn al-Haytham
Read the evidence →

Not a fact anymore

Volcanic eruptions are driven by underground combustion or chemical fires involving substances such as sulfur, coal, or other combustible materials.

What we know now

Volcanoes are driven by molten rock and expanding gases, not by underground fires. Magma forms within Earth and can rise because it is buoyant. As pressure falls during ascent, dissolved gases come out of the magma and expand, sometimes powering explosive eruptions.

Status
Superseded
Accepted for
Not quantified
Changed approximately
Late 18th–19th centuries
Read the evidence →

Not a fact anymore

Widespread domestic-horse mobility was a major driver of the Yamnaya expansion into Europe around 3000 BCE.

What we know now

The Yamnaya were mobile pastoralist communities of the Pontic-Caspian steppe whose ancestry spread widely into Europe around 3000 BCE. Ancient horse genomes place the rapid spread of the lineage that dominates modern domestic horses around 2200 BCE, several centuries later, so large domestic-horse herds cannot explain the earlier expansion in the form once proposed.

Status
Overturned
Category
Archaeology
Accepted for
Not quantified
Changed approximately
2021–2024
Read the evidence →

Not a fact anymore

Wildland fire is always an ecological disaster and healthy landscapes should be protected from every fire.

What we know now

Fire can be destructive, especially when unusually severe or threatening people, but it is also a recurring ecological process in many forests, grasslands, shrublands, and wetlands. Numerous species and ecosystems are adapted to particular fire frequencies, seasons, and intensities.

Status
Narrowed
Category
Ecology
Accepted for
≈80 years
Changed approximately
1950s–1970s
Read the evidence →